Our Story

Graduate from Eastern Washington University in Biochemistry - Biotechnology Program. Four years at the Hutch in Nephrology. Twenty years at AMGEN IMMUNEX specializing in the purification and formulation of biologics and protein reagents from various cell lines in support of AMGEN research groups. Handled molecules surrounding the therapeutic target including the target for antigen or SAR. Specialized in the purification development for large scale rodent and cyno surrogate IgG2 purifications. This included many forms of chromatography and various solutions. Gained experience and expertise in targets for small molecule enzymology from Baculo and mammalian hosts. 

Process Development in the separation development of non-tagged biologics by conventional media techniques. Focused on the early biologic therapeutic for pre PK / tox studies and the surrogate protein counterpart. Modalities included soluble receptors/ligands, Fc fusion therapy, antibody protein, and enzyme proteins. The scale ranged from 1 – 100L fermentation in various host cell lines. I worked to provided formulation strategies in meeting a goal of clean products with the lowest possible level of aggregate and host contaminants. The process strategies were transferred to the engineering colleagues to take the molecule to clinic.