Microbial Expression
Custom protein production: Many proteins, including cytokines, chemokines, and intracellular proteins, can be produced in E. coli at high expression levels. Careful consideration is given to evaluating protein solubility versus insolubility, especially in cases where inclusion bodies are formed, which may require refolding development.
PROCESS
With over 30 years of biotechnology experience, we specialize in biologics optimization and process development. We provide comprehensive support for discovery research, from target identification to biologic product development.
Costs vary based on volume and project complexity. Expression volumes range from 0.5L to 10L, with difficulty determined by refolding efficiency and expression levels. Yields range from 5 to 200 mg per liter.